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New and Notable Evidence 2022
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Trusted evidence. Informed decisions. Better health.

New and Notable Evidence | March 2022

Listing of articles does not imply recommendation.
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Content:

Abortion 

Trials
Analysis on the effect of intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides on hemodynamics and analgesia in pregnant females undergoing painless induced abortion
Wu J, Han Y, Yang L, Liu Z.
Pak J Pharm Sci. 2021 May;34(3(Special)):1249-1254.
PMID: 34602396

Hyoscine butylbromide in pain reduction associated with ultrasound-guided manual vacuum aspiration: A randomized placebo-controlled trial
Jacqueline Pui Wah Chung J, Sze Man Law T, Sze Man Mak J, Chui Yiu Liu R, Singh Sahota D, Chiu Li T, 
Reproductive BioMedicine Online  2022 Feb;44(2):295-303. 
DOI: 10.1016/j.rbmo.2021.10.011. PMID: 34949538


Trial Protocols
Letrozole in Induction of Abortion of Anembryonic Pregnancy
ClinicalTrials.gov: NCT05198050

A Patient Decision Aid for Method of Early Abortion: A Randomized Control Trial
ClinicalTrials.gov: NCT05182008

Contraception 

Trials
Comparison of pain-reducing effect between topical ethyl chloride spray versus subcutaneous 1% lidocaine injection during two rods system contraceptive implant insertion: A randomized controlled trial [FREE FULL TEXT]
Saechoen D, Songthamwat S, Manosomrit T, Chinsri N, Summart U, Songthamwat M.
Eur J Obstet Gynecol Reprod Biol X. 2022 Jan 28;14:100145. 
DOI: 10.1016/j.eurox.2022.100145. PMID: 35141517 

Contraceptive effectiveness, pharmacokinetics, and safety of Sayana® Press when injected every four months: a multicenter phase 3 trial [FREE FULL TEXT]
Deese J, Brache V, Bahamondes L, Salinas A, Jorge A, Veiga N Jr, Fuchs R, Miller A, Taylor D, Halpern V, Dorflinger L.
EClinicalMedicine. 2022 Jan 29;44:101273. 
DOI: 10.1016/j.eclinm.2022.101273. PMID: 35128365 

Evaluation of the impact of humor used in contraception education on the attitudes of university students towards contraceptive methods
Özer B, Yaman-Sözbir Ş.
Eur J Contracept Reprod Health Care. 2022 Feb 2:1-6. 
DOI: 10.1080/13625187.2022.2026324. PMID: 35107401

A randomized double blinded clinical trial to explore the clinical outcomes of vaginal isonicotinic acid hydrazide (INH) administration six hours prior to T380A intrauterine device insertion in persons delivered only by cesarean delivery
Shady NW, Farouk HA, Sallam HF.
Contraception. 2022 Feb 17:9788. 
DOI: 10.1016/j.contraception.2022.01.019. PMID: 35183498

Vitamin B6 Supplementation Reduces Symptoms of Depression in College Women Taking Oral Contraceptives: A Randomized, Double-Blind Crossover Trial
C Curtin A, Johnston CS.
J Diet Suppl. 2022 Feb 2:1-13. 
DOI: 10.1080/19390211.2022.2030843. PMID: 35109763


Trial Protocol
The Pill Project - Oral Contraceptive and Serotonergic Brain Signaling
ClinicalTrials.gov: NCT05212389


Meta-analysis
The effect of oral contraceptive use on cortisol reactivity to the Trier Social Stress Test: A meta-analysis
Gervasio J, Zheng S, Skrotzki C, Pachete A.
Psychoneuroendocrinology. 2022 Feb;136:105626. 
DOI: 10.1016/j.psyneuen.2021.105626. PMID: 34922094 

Family Planning 

Reviews
The effectiveness and characteristics of mHealth interventions to increase adolescent's use of Sexual and Reproductive Health services in Sub-Saharan Africa: A systematic review [FREE FULL TEXT]
Onukwugha FI, Smith L, Kaseje D, Wafula C, Kaseje M, Orton B, Hayter M, Magadi M.
PLoS One. 2022 Jan 21;17(1):e0261973. 
DOI: 10.1371/journal.pone.0261973. PMID: 35061757 

Integration of family planning into HIV services: A systematic review [FREE FULL TEXT]
Nkhoma L, Sitali DC, Zulu JM.
Ann Med. 2022 Dec;54(1):393-403. 
DOI: 10.1080/07853890.2021.2020893. PMID: 35098814 
Listing of articles does not imply recommendation.
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